11/01/2026
What if we could improve heart function by targeting the mitochondria inside heart cells?
Researchers studied SS-31 (elamipretide) in 14 dogs with experimentally induced heart failure. After three months, dogs receiving SS-31 showed improvements in mitochondrial function and the heart’s pumping ability compared with untreated controls.
This is exciting research, but we still need clinical trials in dogs with naturally occurring heart disease before considering SS-31 an established treatment.
The future of veterinary medicine is exciting as we continue exploring the capabilities of these peptides!
Research: Sabbah HN et al. Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure. Circulation: Heart Failure. 2016;9:e002206.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4743543/