08/01/2025
⏳🧬 Why Timing Matters: What the Research Really Says About Early Spay & Neuter✂️
As loving pet parents, we all want to do what’s best for our dogs — and that includes making the right decision around spay and neuter.
For years, early des*xing (before dogs reach s*xual maturity) has been widely promoted as standard practice — often as early as 8–16 weeks in rescues or before a first season in females. But emerging research over the past decade is prompting a much-needed rethink.
Here’s what the science is showing us.
⏱️ What Does “Early” Really Mean?
“Early spay/neuter” typically refers to des*xing before the dog is hormonally or skeletally mature. That means:
🔹 Females: Spayed before their first season — often under 12 months
🔹 Males: Neutered before 12–18 months, depending on breed size
But these are the very life stages when s*x hormones like oestrogen and testosterone are doing critical work — not just for reproduction, but for bone growth, immune development, mental resilience, and long-term disease prevention.
🔍 So, What Did the Research Actually Find?
Several large-scale, peer-reviewed studies have shown links between early des*xing and increased risk of:
🦴 Joint disease and poor skeletal development
• Early des*xing delays growth plate closure, increasing the risk of hip dysplasia, elbow dysplasia, and cruciate ligament tears — especially in medium to large breeds.
• One UC Davis study (Hart et al., 2020) found that neutering male Golden Retrievers before 6 months tripled their risk of joint disorders.
🧬 Increased cancer risk
• Early neutering has been associated with a higher incidence of certain cancers, including hemangiosarcoma, lymphoma, and osteosarcoma.
• Vizsla-specific research (Zink et al., 2014) showed that spayed females were 9x more likely to develop hemangiosarcoma than intact females.
🧠 Behavioural and cognitive changes
• Early spay/neuter has been linked to increased risks of fear, reactivity, and noise sensitivity, especially in females spayed before maturity.
• This may be due to the loss of s*x hormones that influence brain development and emotional resilience.
🦠 Immune dysregulation and chronic disease
• Early removal of s*x hormones affects the endocrine system and may play a role in autoimmune disease risk, urinary incontinence (especially in females), and even cognitive decline in older dogs.
📚 Just a Handful of the Studies Behind These Findings:
• Hart, B.L. et al. (2020) – UC Davis 35 breed study
DOI: 10.3389/fvets.2020.00388
• Torres de la Riva et al. (2013) – Golden Retrievers
DOI: 10.1371/journal.pone.0055937
• Zink et al. (2014) – Vizsla Health Study
• Root Kustritz (2007) – Review of gonadectomy timing
DOI: 10.2460/javma.231.11.1665
• O’Neill et al. (2021) – UK VetCompass longevity data
DOI: 10.1136/vr.105828
And many more studies continue to support a breed-specific, age-appropriate approach to des*xing.
💡 So What Are the Options?
We understand there are situations where spay/neuter is necessary — for example, in rescue dogs or to prevent accidental litters. But there are options that preserve your dog’s hormones longer while still preventing pregnancy:
✅ Chemical castration (Suprelorin) – a reversible implant that allows males to mature before permanent castration
✅ Ovary-sparing spay (OSS) – removes the uterus but preserves the ovaries and natural hormones
✅ Vasectomy – blocks s***m without removing testosterone-producing te**es
These approaches can allow dogs to develop normally before decisions that affect their lifetime health are made.
💊 What If My Dog Was Already Des*xed Young?
If your dog was spayed or neutered early — don’t panic. You didn’t do anything wrong. You made the best decision you could with the information you had.
But there are things we can do now to support their health:
🌿 Consider discussing bioidentical hormone replacement therapy with a reproductive or integrative vet
🐕 Support their joints, hormones and immunity with:
• Omega-3 fatty acids
• Bone broth & collagen
• Antioxidant-rich foods
• Endocrine support supplements
We’re happy to recommend brands we trust.
🐾 Final Thoughts
This isn’t about creating fear or guilt — it’s about equipping you with science-led knowledge so you can make informed choices for your dog.
As we learn more about how vital natural hormones are to your dog’s long-term health, it’s clear that when we spay or neuter matters just as much as whether we do.
❤️ At Poochie Park & Pantry, we’re here to support you with holistic, evidence-led information — no judgment, just help.
Have questions or want to explore safer options for your pup? Just reach out — we’re happy to chat.