The Perseus Foundation

11/12/2025

11/12/2025

Warm congratulations sweet Milo 👏 We are rooting for you❤️😘🐾!!!

Thank you SAGE Veterinary Centers for your excellence in care.

https://www.facebook.com/share/p/1A65X6uU4N/?mibextid=wwXIfr

Meet Milo! 🐾 This 8-year-old Beagle was treated for a progressive facial mass with stereotactic radiation (SRS/SRT) by the PetCure Oncology Team at SAGE Veterinary Centers

Milo was just told that his graduation party will be next door at the PetHero Hall of Fame 🎪

Congratulations, Milo! 🎉

👉 Drop a 🎪 or 🐶 to congratulate Milo

11/11/2025

🌟 🎊Happy Veterans Day! 🇺🇸 Today, we honor our courageous veterans and their commitment to our freedom. We salute not only the brave individuals but also the Military and Contract Working dogs who stand by their side. A ❤️ thank you for your service. 🐾❤️🐾💙🐾

11/11/2025

Dog breeds most prone to cancer include Boxers, Bernese Mountain Dogs, Golden Retrievers, Rottweilers, and German Shepherds. Other breeds with a higher risk are the Great Dane, Flat-coated Retriever, Scottish Terrier, and Poodle. The specific types of cancer vary by breed, and a veterinarian should be consulted for preventative care.

Common breeds at high risk

Boxer:
Prone to cancers like hemangiosarcoma and mast cell tumors, and also have a higher risk of skin cancer due to sun exposure.

Bernese Mountain Dog:
High risk for various cancers, including mast cell tumors and hemangiosarcoma.

Golden Retriever:
Often diagnosed with hemangiosarcoma, lymphoma, and osteosarcoma.

Rottweiler:
High risk for bone cancer, lymphoma, and hemangiosarcoma.

German Shepherd:
Prone to hemangiosarcoma, mast cell tumors, and osteosarcoma.

Flat-coated Retriever:
Highly susceptible to a specific type of sarcoma.

Scottish Terrier:
Have a higher incidence of bladder cancer and histiocytic cell tumors.

Poodle:
Prone to mammary tumors and histiocytic cell tumors.

Beagle:
Prone to lymphoma, osteosarcoma, and bladder cancer.

Great Dane:
Higher risk for osteosarcoma and m

11/10/2025

New canine cancer treatments include personalized medicine using genetic testing (like FidoCure), chemo-immunotherapy (like ECI), and innovative targeted therapies such as CAR T-cell therapy, inhaled immunotherapy, and injectable radio gel. These approaches aim to improve outcomes by using a dog's own immune system or by precisely targeting cancer cells with newer drugs, vaccines, and radiation methods.

Targeted and personalized medicine
Genetic testing: Some services use genetic sequencing of a dog's tumor to identify specific mutations and recommend targeted therapies, a form of precision medicine.
Targeted molecular therapy: Clinical trials are testing drugs like ibrutinib and acalabrutinib for certain lymphomas, as well as other antibody-based therapies for specific cancers like oral malignant melanoma and undifferentiated sarcoma.

Immunotherapy
Chemo-immunotherapy: A new approach combines a single dose of chemotherapy with an immunotherapy called ECI, which enhances the dog's own immune response to destroy cancer cells. This has shown promise for bone cancer (osteosarcoma).

CAR T-cell therapy: In a novel approach, T-cells are engineered to recognize and attack cancer cells. These cells are injected directly into the tumor's lymph nodes to more effectively destroy cancer cells, with some dogs entering complete remission.

Vaccine therapy: Researchers are developing cancer vaccines that can double the one-year survival rate for dogs with aggressive forms of cancer.

Inhaled immunotherapy: This method involves delivering immunotherapy (like interleukin 15) as a breathing treatment directly into the lungs to concentrate the therapy where lung cancer has spread.
Other innovative treatments

Radio gel: This involves injecting a radioactive gel directly into the tumor. The gel delivers a high-energy dose of radiation that travels only a short distance, destroying cancer cells with limited side effects and potentially offering a targeted radiation option.

Xenogeneic CAR T-cell therapy: This uses human CAR T-cells that are engineered to kill dog cancer cells, which allows the cells to be manufactured in large quantities and kept on hand for any dog that needs them.

11/10/2025

https://news.cuanschutz.edu/cancer-center/baxter-sinonasal-carcinoma?fbclid=IwZnRzaAN_EU9leHRuA2FlbQIxMQBzcnRjBmFwcF9pZAo2NjI4NTY4Mzc5AAEef4DmDHm8oYtgl4SIVGNSlxEhatLrinxArGmY668obOeNEEpDsmaSEIbTL3E_aem_A4gjtTFVXn2SE2tZ6Ooe0Q

Follow Baxter’s inspiring fight against nasal cancer through a CSU clinical trial, advancing treatments for pets and humans alike.

11/09/2025

🐾Onco Bits of Information🐾

11/09/2025

When clients hear electrochemotherapy, they often imagine “shock therapy” — but the reality is far more refined, targeted, and full of potential.

In this episode of the Veterinary Cancer Pioneers Podcast, Dr. Rachel Venable sits down with Dr. Joseph Impellizeri, Director of the Barrymore Center for Advanced Cancer Care and a leader in electrochemotherapy and gene electrotransfer immunotherapy.

Dr. Impellizeri shares how electroporation-based treatments are transforming cancer care — allowing localized chemotherapy and immunotherapy delivery with minimal side effects. He discusses its expanding applications beyond skin tumors to complex oral, nasal, and bone cancers, and how it integrates with surgery, chemotherapy, and radiation for improved outcomes.

The episode also explores his pioneering work combining gene electrotransfer with PD-1 inhibitors, offering a glimpse into the future of precision oncology and more compassionate, personalized care.

🎧 Watch the full episode:

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Joseph Impellizeri, a true trailblazer in targeted electroche...

11/09/2025

Receiving a diagnosis of cancer can often be unexpected, and your primary care veterinarian may recommend referral to an oncology specialist. Friendship Oncology Specialists (FOS), located in Washington, DC is here to help and provides state-of-the-art treatment options for pets with cancer. Recent advances in diagnostic and treatment capabilities have allowed for a more individualized approach to veterinary cancer care, leading to more successful outcomes.

Friendship Hospital for Animals thank you for providing outstanding care through the years tothousands of cancer patients🐾⭐️❤️

https://www.friendshiphospital.com/pet-owners/oncology/

11/08/2025

Meet Adorable Bristol! 🐾 He was treated for an AGASACA (Apocrine Gland A**l Sac Adenocarcinoma) with stereotactic radiation (SRS/SRT) by the PetCure Oncology Team at BluePearl Pittsburgh Pet Hospitals

Warmest Congratulations, Bristol! 🎉

👉 Drop a 🍂 or 🐶 to congratulate Bristol

11/06/2025

From the Desk of Dr Sue Cancer Vet ✍️

If your pet was recently diagnosed with cancer and you’re in talks with your veterinarian about chemotherapy, I want you to take a deep breath. 😮‍💨⁠
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I know the word ‘chemotherapy’ can evoke a range of emotions, mainly fear, but in veterinary medicine, the side effects are different from those in human oncology.⁠
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🔹 In fact, about 80% of dogs and 90% of cats experience minimal side effects from treatment.⁠
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🔹 Less than 25% of pets will experience a mild side effect (like temporary diarrhea, mild vomiting or nausea, or decreased appetite).⁠
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🔹 And about 5-7% will experience any severe side effects.⁠
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Sometimes we’ll prescribe anti-anxiety medication at home or use light sedation for patients who are especially nervous, but most pets don’t need it. ⁠
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The majority of pets tolerate treatment quite well and remain happy and comfortable.⁠
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🎯 Our goal is always quality of life, not just time, which means choosing protocols that allow your pet to feel well while treating their disease safely and effectively.⁠
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If you’re navigating this right now, I hope this brings you some relief.⁠
I’m here to guide you every step of the way. 💙⁠
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11/06/2025

Calviri's new blood test, 🩸StageOne Plus, is a promising tool for detecting canine hemangiosarcoma, while other research focuses on developing tests using microRNAs and investigating other biomarkers. These new tests aim to enable earlier detection than traditional methods, which often rely on imaging and physical examination, but are still in various stages of development and not yet widely available.

New blood tests 🩸

➡️Calviri's StageOne Plus: This test analyzes a blood sample on peptide chips to detect cancer. It is designed as an affordable diagnostic tool for annual wellness checkups in dogs and has been available in limited veterinary clinics since August 2025.

➡️Nu.Q Vet Cancer Test: This test can detect certain cancers, including hemangiosarcoma, even at early stages, and is being developed to assist with cancer screening.

➡️miRNA biomarker research: Researchers at Cornell University College of Veterinary Medicine and Purdue University are working on a diagnostic test for canine hemangiosarcoma using a panel of unique microRNA biomarkers identified in blood samples.

Other diagnostic research
Bio-detection dogs: Research is being conducted to identify the specific volatile organic compound (VOC) profiles associated with hemangiosarcoma using bio-detection dogs as a step toward developing a new diagnostic test.
Other biomarkers: Researchers are investigating other potential biomarkers, such as circulating nucleosomes and the enzyme thymidine kinase (TK), for use in hemangiosarcoma diagnosis and treatment monitoring.
HeLP and T-STAT scores: These tools use a variety of clinical parameters to help predict the likelihood of hemangiosarcoma in dogs.

What this means for dog owners
While these new tests offer hope for earlier diagnosis, they are still in various stages of research and development.

Some, like Calviri's StageOne Plus, are becoming available at a limited number of veterinary clinics.

Speakwith your veterinarian about the most appropriate diagnostic options for your dog, especially if your dog is in a breed at higher risk for hemangiosarcoma.