01/20/2026
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Foals are born agammaglobulinemic, meaning they have no circulating antibodies at birth and are entirely dependent on adequate colostrum intake for passive immunity. When insufficient antibody absorption occurs, Failure of Passive Transfer (FPT) develops, significantly increasing the risk of infectious disease in the neonatal period.
Plasma transfusion is a critical therapeutic and preventive intervention in these cases. Administered intravenously, equine plasma provides immunoglobulins that help establish immune protection, reducing the risk of serious conditions such as sepsis, pneumonia, and enteritis, while supporting overall neonatal health.
Plasma is not reserved solely for critically ill foals! In many breeding programs, plasma is routinely administered to healthy newborn foals as a proactive measure to enhance immune defense during the first days of life. This approach is especially valuable when colostrum quality, intake, or timing is uncertain, or when foals are considered higher risk due to environmental or management factors.
Plasma therapy may be used in cases of:
βΎοΈNeonatal foals with diagnosed Failure of Passive Transfer (FPT)
βΎοΈSick or immunocompromised foals requiring immune support
βΎοΈSelect healthy neonates as a proactive measure when colostrum intake or quality is questionable
Discussing neonatal care and plasma availability with your veterinarian before foaling allows for prompt decision-making during this critical window of life. Have questions about plasma therapy or the products we offer? Our team is happy to help!