01/13/2026
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Rhodesian Ridgebacks & Dermoid Sinus
Recently on a post about how we normalise extreme conformation. We asked people to give examples of animals with conformation that we normalise that we shouldn't. Rhodesian Ridgebacks & Dermoid Sinus was mentioned. For the purpose of this, we could also consider the Thai Ridgeback.
Lets investigate...
Rhodesian Ridgebacks are well known for their distinctive line of hair running along the spine — the dorsal ridge.
Fewer people realise that the same developmental abnormality that creates the ridge also predisposes these dogs to a condition called dermoid sinus.
What Is Dermoid Sinus?
Dermoid Sinus presents as a tubular skin indentation to variable degree into underlying tissues on the dorsal midline or cranial or caudal to the ridge, present from birth. A recent study stated there was a 'complex genetic basis for this condition'
These tunnels can:
➡️ remain shallow
➡️ extend deep into tissue
➡️ in the most severe cases (Category IV), connect directly to the spinal cord
How Common Is It?
In Sweden, 8–10% of Ridgebacks were reported affected, and prevalence was increasing (Salmon Hillbertz 2005). More recent data from Germany (12,700 puppies, 2001–2019) shows 2.53% prevalence, (litter with only ridged animals, prevalence was 2.81%.)
The Genetics — More Complex Than Once Believed
Historically, dermoid sinus was thought to be inherited in a simple way. As it was thought to be simple autosomal dominant mutation, one paper stated 'Because this disease is considered inherited in Rhodesian Ridgebacks, affected animals should not be bred.' However, research (see below) did more work to investigate the complexity of dermoid sinus.
The dorsal hair ridge in ridgeback dogs was found in a 2007 paper to be caused by a '133 kb duplication of three fibroblast growth factor genes FGF3, FGF4 and FGF19 and the ORAOV1 gene.' It stated that 'dogs homozygous for this copy number variation mutation have an increased risk of developing Dermoid Sinus (DS)'. They stated that 'further studies regarding the genetic complexity of DS and LTF will shed light on the biological complexity of these dermal lesions.'
Research (2022) did more work to investigate the complexity of this. It found:
✔ Inheritance of DS does not fit a simple autosomal recessive model
✔ The genetics of DS appear complex
How Serious Is It?
The welfare impact varies depending on the type of sinus:
🔴 Category IV (highest risk):
• Infection can spread to the spinal cord
• Causes severe pain, neurological disease, or paralysis
(In some dogs, these sinuses pe*****te through the vertebral lamina and Into the dura mater, predisposing the animal to infection and neurologic abnormalities.)
• May lead to death or euthanasia if not treated urgently
• One article stated 'Currently, it is the policy of some breeders to euthanase affected puppies shortly after birth' - we are unsure how common this occurs now.
🟠 Other forms:
• Recurrent infections
• Chronic pain and discomfort
• Need for surgical removal
📖 References
Prevalence and segregation analysis of dermoid sinus in Rhodesian Ridgebacks, Ottmar Distl, The Veterinary Journal, 2022.
https://www.sciencedirect.com/science/article/abs/pii/S1090023322000181
Universities Federation for Animal Welfare, Rhodesian Ridgeback, Dermoid Sinus
https://www.ufaw.org.uk/dogs/rhodesian-ridgeback-dermoid-sinus
Miller, Lisa & Tobias, Karen. (2003). Dermoid sinuses: Description, diagnosis, and treatment. Compendium on Continuing Education for the Practicing Veterinarian. 25. 295-300.
Salmon Hillbertz NH, Isaksson M, Karlsson EK, Hellmén E, Pielberg GR, Savolainen P, Wade CM, von Euler H, Gustafson U, Hedhammar A, Nilsson M, Lindblad-Toh K, Andersson L, Andersson G. Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs. Nat Genet. 2007 Nov;39(11):1318-20. doi: 10.1038/ng.2007.4. Epub 2007 Sep 30. PMID: 17906623.
Salmon Hillbertz, Nicolette. (2007). The origin of the ridge and associated anomalies in Rhodesian Ridgebacks.