01/30/2026
I caution clients about this all the time, I know it’s easier to prep things for ourselves and for others who are caring for our animals, but it could have devastating consequences.
Did you know that Prascend (and all forms of pergolide) tablets are unstable once taken out of their special nitrogen-filled foil compartment?
Some horse owners mistakenly take them out of the packaging ahead of time for convenience, which can lead to rapid degradation. Another dilemma is when horses are supposed to get a partial tablet. What's the best practice?
The very best option for storing partial pergolide tablets is to keep them in their original nitrogen-flushed blister packs until the moment of administration to prevent rapid degradation from light and other factors.
If a tablet must be split, store the unused portion in a small, sealed, dark container with a silica gel packet.
Store in Dark/Cool Location: Keep the container away from direct sunlight and in a cool, dry place (at or below 77°F/25°C).
Time Limit: Use the partial tablet within 24 hours to ensure effectiveness.
Alternative - Foil: Some owners tightly wrap the unused, halved tablet in aluminum foil and store it in a small, sealed container.
Do not pre-cut tablets for more than one or two days in advance.