水中秘境 Crystal shrimp

25/01/2023

25/01/2023

以色列金蠍（學名：Leiurusquinquestriatus）是屬於蠍目鉗蠍科的生物，也稱為巴勒斯坦黃蠍、巴勒斯坦毒蠍、以色列殺人蠍，顏色約為黃色，身長三至八公分，平均約六公分。擁有能致人於死的劇毒，分布於北非至印度的沙漠地區。

2023以色列金蝎，目前技術：突破抗寒與休眠狀態，成長率突破80%~90%。

這次研究，技術無保溫，據抗寒，體型比原生種，提升0.3＞0.8mm。

毒素量提升:0.02＞0.05mg
蠍氯毒素（英語：Chlorotoxin）
卡利蠍毒素（英語：Kaliotoxin）

預期體型提升7至8齡約：
公蠍:0.5公分＞1.2公分。
母蠍：0.8公分>2.公分。

研究價值
編輯
其毒液富含蠍氯毒素能辨認腫瘤及脊椎腫瘤，還可用以治療瘧疾；卡利蠍毒素可用以治療老鼠骨骼疾病。 毒液採集需採用人工手擠，每隻金蠍僅能生產2 mg毒液，一加侖價值4,900萬美元。

外部連結
編輯
Leiurus Quinquestriatus, WikiPets
好毒！世上最貴的液體 1公升值3億（頁面存檔備份，存於網際網路檔案館）

14/07/2022

Scolopendra subspinipes multidens

Medicinal and economic value of centipede

1. Modern pharmacological studies have shown that centipedes contain two bee venom-like components with high therapeutic value, namely histamine-like substances and hemolytic proteins, as well as fatty oils, cholesterol, formic acid and other active substances, which can also be isolated. S-hydroxylysine, glycine, alanine, glutamic acid and other amino acid components. Therefore, the medicinal value is very high.

2. Centipede is acrid and warm in nature, poisonous, and has various effects such as expelling wind, relieving spasm, attacking poison, dispersing knot, dredging collaterals, relieving pain, killing insects, reducing swelling, detoxifying blister, anti-tumor and anti-fungal. It can treat a variety of diseases such as stroke, migraine, convulsions, tetanus, whooping cough, scrofula, tuberculosis, crux, tumor, sore, swollen poison, rheumatism, snakebite, hemorrhoids, etc. one.

3. Centipede has high medicinal value and economic value. As a traditional Chinese medicine, centipedes were mostly caught in the wild in the past. In recent years, with the intensification of environmental pollution, people's indiscriminate fishing and the continuous expansion of the scope of application, the wild centipede resources are becoming more and more depleted, and the supply of centipedes appears to be very short. Therefore, Breeding centipedes is a good way to get rich.

26/08/2021

After scientists discovered last month that scorpion venom can help doctors find the location of brain tumors more easily, this time the US and Mexican teams have identified new applications of scorpion venom. They found two types of scorpion venom that can kill Staphylococcus aureus and tuberculosis. In addition to bacillus compounds, scientists have also successfully synthesized key elements in the laboratory, eliminating the need to frequently use expensive and rare scorpion venom. Scorpion venom is an offensive and defensive weapon for scorpions for food and defense. It contains many neurotoxins and cytotoxins. At first glance, it is not a good doctor. However, as scientists continue to research and analyze, they gradually discover the neuromolecules and molecular immunity in the venom. , Protein structure, etc. are of great help to the medical field, in fact, it is a good source of life-saving medicine.
This time, Stanford University, the National University of Mexico, and the Salvador Zubirán National Institute of Health Sciences and Nutrition of Mexico worked together to study the venom of the scorpion Diplocentrus melici from Mexico.
The research was first initiated by the National University of Mexico. When the team studied Diplocentrus melici earlier, they found that their venom would change from transparent to brown when exposed to air. After further research, it was determined that two of these compounds were the key to everything. They can turn the venom into blue and red respectively. This discovery aroused the curiosity of the National University of Mexico team and decided to solve the mystery behind the team with Stanford University.

After Stanford University took over, through analysis of 0.5 microliters of venom, which was less than mosquito blood, it was found that these two mysterious substances are unprecedented new types of benzoquinone (Benzoquinone). The development of antibacterial drugs is of great benefit. The team is also replicating the compounds of scorpion venom in the laboratory and beginning to explore what kind of drugs they are suitable for.
After being handed over to the National Institute of Health Science and Nutrition in Salvador Zubirán, Mexico, the team found that red benzoquinone can effectively kill Staphylococcus aureus, and blue benzoquinone can eliminate tuberculosis bacteria. Scientists have also found that these compounds are not effective in animal experiments. It affects the lung epithelium of the mice, and the mice have no adverse reactions, and they have the opportunity to become a new drug candidate.
Among them, Mycobacterium tuberculosis is the causative agent of tuberculosis. It usually becomes a lung infection, which is the notorious tuberculosis. It is currently the infectious disease with the largest number of illnesses and deaths in Taiwan. After the first infection with tuberculosis, the chance of reactivation and disease in the whole life About 5 to 10%, even if cured, they still have to be tracked continuously; Staphylococcus aureus is a common pathogen that causes food poisoning. It is resistant to antibiotics and causes a strong inflammatory response. When the immune system is weakened and infected with multiple drug resistances Staphylococcus aureus is life-threatening.
So these two benzoquinones may become someone’s heroes in the future, but scientists still don’t know whether these two compounds are life-saving drugs or double-edged swords. The author of the paper and Professor of Chemistry at Stanford University Richard Zare said that these compounds can kill. Dead bacteria, but on the other hand, they may also be harmful to the human body. Therefore, it is necessary to continue research and experiment before actually using Staphylococcus aureus and Mycobacterium tuberculosis drugs.
Fortunately, the scientific team has previously successfully decomposed the compound and understood how to synthesize it. Otherwise, the venom is one of the most precious materials in the world. For Deathstalker Scorpion, a gallon of venom is asking for 39 million U.S. dollars (approximately NT$1.2 billion). It is a very important research process to determine the key ingredients and how to synthesize them.

25/08/2021

En 2021, de juillet à août, se sont précipités pour concevoir artificiellement.Deux groupes de dos dorés israéliens et de scorpions noirs turcs se sont accouplés en seulement 2 mois, 3 paires de scorpions à valeur médicale.

In 2021, from July to August, the artificial insemination was rushed. Two groups of Israeli golden backs and Turkish black fat scorpions were mated in just 2 months. There were 3 pairs of scorpions with medical value.

crassicauda
quinquestriatus

05/08/2021

I am the biggest breeder of scorpions, 【Israeli Golden Scorpion】
It's not that I like scorpions, but I want to produce them in large quantities.

This year, the American Human DNA Research Corporation announced that it will not export all Israeli gold scorpions and toxin materials.

I just found a few friends from the AI ​​medical company to pass on my four years of research and reproduction technology and mass-produce them. They can make breakthroughs and treat all the raw materials that are harmful to human health.

In the future, cancer can be self-treated no matter what, there are many, many, breakthrough and effective self-treatment of many diseases.

In the summer of the second half of 2021, the output value is less than that in the winter of the first half of this year.
Scorpions do not need to be cared about, but they still need to reproduce technically.

Many invisible industries in Taiwan are not lost to the world.

I am thinking that it will take 5 years at the earliest to have so many raw materials

Five years sounds like a long time, but to me, time is very urgent.

Extremely expensive, meaning: the current American examiner will cost 1.5 billion Taiwan dollars for 1 gallon/3.8 liters in 2021.
Extremely dystocia, meaning: mating is artificial mating. During the mating process, sometimes the female scorpion will kill the male scorpion for 6 to 28 hours, and the mating may not produce birth. Successful conception will also lead to the female scorpion and the embryo is immature.
Extremely precious, meaning: it may not be able to feed. Generally, it is difficult for living organisms to control death. The demand will be large in the future and the price will be higher.

Don't think that he is not dangerous. Current research reports that it is about 6 cm, about 4 to 6 liters, which can kill children and the elderly. The middle age is about 18 to 40, and it is very dangerous to be stabbed.

08/07/2021

The deathstalker is one of the most dangerous scorpions on the planet, and its venom is also the most expensive liquid in the world at $39 million per gallon.

But it's not so simple to just buy a gallon — you'd have to milk one scorpion 2.64 million times to fill a gallon.

See more stories on Insider's business page.

Following is a transcript from the video:

Narrator: The deathstalker is one of the most dangerous scorpions on the planet, and what makes it so dangerous also happens to be the most expensive liquid in the world. This stuff costs $39 million per gallon. Now, even if you had the money, you couldn't just go and buy a gallon of the stuff, because you can only get it in tiny, minuscule amounts. $130 will get you a droplet that's smaller than a grain of sugar.

The reason why is pretty simple: the stuff is hard to get. Scorpions are almost always milked by hand, one by one. And one scorpion produces, at the most, just two milligrams of venom at a time.

So, let's do the math. If you owned one scorpion you would have to milk it 2.64 million times to fill a gallon. And let's face it, you'd probably get stung along the way as well. One sting isn't enough to kill a healthy human, but I think it hurts.

Steve Trim: I'd easily put it being a hundred times more painful than a bee sting, but because pain is a subjective and emotional experience, it's difficult to really get a quantification on that. But it's definitely gonna ruin your day.

Narrator: That's Venomtech founder Steve Trim, one of the few people brave enough to deal with these animals. That's because inside that deadly venom, there's actually tons of useful components that are helping pioneer breakthrough medicines.

Chlorotoxins, for example, are the perfect size to bind with certain cancer cells in the brain and spine, which is helpful for identifying the specific size and location of tumors. And researchers have used scorpion to eliminate malaria in mosquitoes. Kaliotoxin has been given to rats to fight bone disease. Scientists hope it could work in humans too.

These are just a few of the medical benefits that researchers have found in scorpion venom. And the more they research it, the more uses they find. Which means demand for this miracle venom continues to grow. So scientists are now trying to figure out ways to get more of it faster.

01/07/2021

LD50意思：
半數致死量（英語：Median Lethal Dose），簡稱LD50（即Lethal Dose, 50%），在毒理學中是描述有毒物質或輻射的毒性的常用指標。按照醫學主題詞表（MeSH）的定義，LD50是指「能殺死一半試驗總體之有害物質、有毒物質或游離輻射的劑量」。這測試最先由J.W. Trevan於1927年提出。

(Lethal Dose,50%)半數致死劑量 - 能殺死一半試驗總體之有毒物質的劑量
(單位：mg/kg) 數值愈低毒性愈強

以色列金蠍又稱以色列殺人蠍，毒性LD50值是:0.16-0.50，為全球排名蠍子中數一數二，最毒物種。2018美國醫學週刊。
（一加侖，台幣13億多）

眼鏡王蛇毒液的毒性測試結果在不同的毒理學研究中都有不同，因為LD50數據會隨著不同的注射及研究方法而產生變化。實驗白鼠皮下注射的1.7 mg/kg

用最毒的毒蛇跟以色列金蝎

眼睛王蛇：1.7 mg/kg

以色列金蝎：0.16mmg/kg

研究很久，以40隻以色列金蝎會有3～6隻，黃金色。

26/06/2021

在繁殖，以色列金背蠍子
他的毒液目前全世界最貴的液

被以色列金背蝎，扎一下
運氣好一點，只在加護病房
所以復育中要找到抗血清毒素。

學 名：Androctonus crassicauda
(Olivier, 1807)

英 名：Turkey Black Fat-Tail Scorpion、Arabian Fat-Tailed Scorpion

別 名：阿拉伯肥尾蠍

科 名：鉗蠍科(Buthidae)

分 布：北非、埃及與中東；棲居在乾燥且植物稀少的沙漠與半沙漠地區。

土耳其黑肥尾蠍在台灣與中國大陸的寵物市場中一直被視為珍品，除了因為少見之外，其霸氣的體型加上相當強大的毒性也成為蠍迷的收藏目標之一，但是由於牠們懷有劇毒與可注射相當多量的毒液，國外有個專業的蠍子飼養家評價土耳其黑肥尾蠍的危險度僅次於以色列金蠍(Leiurus quinquestriatus)，加上個性非常暴躁，實在不是一個初學者適合接觸的蠍種。

形態特徵：體長通常為8～10公分，某些個體可超過10公分，體色可能是褐色、深褐色至黑色，全身具有類似金屬般的反光光澤，粗壯肥大的尾部長滿了偵測剛毛，身體的某些稜脊佈有粗糙的顆粒，與粗大的尾部相比，螯肢相對較小。

該物種的LD50為 0.08 mg/kg (IV) 和 0.40 mg/kg (SC)

※附 註：自 1942 年以來，該物種產生的抗蛇毒血清已在土耳其用於治療所有蝎子叮咬。
（有很高的藥用價值）

21/06/2021

https://www.discovermagazine.com/planet-earth/whats-so-special-about-the-deathstalker-scorpion

How an obscure arachnid from the deserts of the Middle East and Northern Africa rocketed to media stardom, and has even saved lives.

21/06/2021

Water secrets, transformation, cancer raw materials, cooperation with Taiwan AI company, development, Israeli golden scorpion, raw materials, a large number of artificial professional breeding, leading breeding technology.