
22/08/2025
Anti-cocci Toxicity in Dogs
Recently weve had cases of suspected ionophore toxicity, following the ingestion of calf milk replacer or meal including anti-cocci. Now that calving is in full swing, the presence of anti-cocci on farm is increasing. We would like to make you aware that anti-cocci (ionophore) is toxic to dog, such as monensin (Rumensin) or lasalocid (Bovatec). Other sources of ionophores include certain types of chicken feed, bloat capsules and feed additives like Rumensin. Cattle and other ruminants are able to digest and process these ingredients safely, but monogastric species can’t (dogs, horses and pigs).
Ionophore toxicity affects skeletal muscles and heart muscle, causing paralysis. Signs develop within 4 - 12 hours of ingestion. This can look like generalised weakness and a staggering walk. Other more subtle signs are dilated pupils, increased heart rate and breathing rate. Weakness often starts in the hindlimbs, but gradually affects the whole body, resulting in an inability to walk. In the worst cases animals can develop heart failure and some may even die from respiratory failure. Animals that manage to recovery from an acute toxic exposure could be left with permanent damage to their muscles and heart.
Prevention is better than cure! Preventing exposure to this toxin is the best way of avoiding problems, by making sure dogs are not getting access to left over milk replacer or meal including anti-cocci. Unfortunately, there is no specific treatment or antidote to Ionophore toxicity. If you notice or are suspicious that your dog has eaten anti-cocci then please ring for us to intervene as soon as possible! Removing the toxin from their stomach and giving charcoal to reduce absorption is possible. The sooner this can be done, the better the chance of success! This is definitely an emergency!
Please have a careful look to see if you have products containing ionophores on your property. If you do, please ensure they are kept out of the reach of dogs.
Happy calving!