
17/06/2025
【Long-term Outcome of Mitral Valve Repair】
先日ご報告いたしました僧帽弁修復術の短期成績に続き、1,019頭の長期予後を追跡した解析結果がJournal of Veterinary Internal Medicineに掲載されました!
🔎研究のポイント
- アウトカム:全死亡、術後うっ血性心不全の発症
- 術後早期(100日未満)と遠隔期(100~1,400日)で解析
- 術後早期は遠隔期に比べてイベント発生率が高い
- 術後早期のリスク因子:Stage D(vs. B2)、手術年次
- 術後遠隔期のリスク因子:年齢、体重、キャバリア、TRV>3.7 m/s
術後早期ではStage Dが予後に大きく影響しましたが、遠隔期ではステージによる差はみられませんでした。犬種や肺高血圧の存在などが長期予後に関係している可能性があり、今後さらなる研究を進めていきたいと考えています。
We’re excited to share that our study on LONG-TERM outcomes following mitral valve repair in 1,019 dogs is now published in the Journal of Veterinary Internal Medicine!!
🔍Highlights
- Outcomes: all-cause mortality and post-op congestive heart failure
- Separate analyses for early (3.7 m/s
While Stage D was a significant risk factor for early postoperative events, no clear difference was seen among stages during the late period. Breed and pulmonary hypertension may be key factors in long-term prognosis, and we hope to explore these further in future studies.
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K. Kurogochi, S. Furusato, E. Takahashi, et al., “ Long-Term Outcomes of Mitral Valve Repair With Artificial Chordae and Annuloplasty for Myxomatous Mitral Valve Disease in Dogs,” Journal of Veterinary Internal Medicine 39, no. 4 (2025): e70171.
Background Myxomatous mitral valve disease (MMVD) in dogs commonly progresses to congestive heart failure, which carries a poor prognosis. Mitral valve repair (MVR) is a recognized treatment for adv...