20/10/2026
Following her shunt surgery, Misty unexpectedly developed severe neurological complications, becoming confused and experiencing muscle tremors and seizure-like activity. Blood tests confirmed her ammonia levels were completely normal. Instead, she was experiencing Post-Attentuation Neurological Syndrome (PANS) - a rare and complex complication where the brain reacts to the sudden restoration of normal blood flow.
Because her symptoms were severe, Misty was immediately transferred to our Emergency and Critical Care (ECC) team for intensive 24/7 care. As her condition progressed, she temporarily lost consciousness and required a breathing tube to protect her airway, anti-seizure medications, and a temporary feeding tube for nutrition.
To give Misty the best possible chance of recovery, our multidisciplinary team performed an advanced treatment called Therapeutic Plasma Exchange (TPE). This process allows us to separate and remove a portion of the patient's blood plasma and replace it with donor plasma, helping to clear substances that may be irritating the brain.
Following TPE, Misty made a remarkable turnaround! Day by day, she became more alert, regained her balance, and started standing, walking, and eating independently again. After two weeks of round-the-clock intensive care, Misty had made such incredible progress that she was ready to continue her recovery at home!
Misty was discharged to her carers with anti-seizure medication, gut support, and a Purina HA diet to keep her liver comfortable as the cellophane band continues its work. While she retains a mild visual impairment, her mobility and personality have returned, and she will be back to see our Soft Tissue Surgery team in two months for a routine recheck.
Check back tomorrow for a special reflection from Nurse Alexa on Misty’s journey with us 💙