09/07/2026
🤩 Exciting news! 🤩
We are continuing to expand what we can offer our clients and their horses, and our latest addition to the kit is the Alpha-2 Macroglobulin centrifuge. Orthobiologics is being used more frequently in human and equine medicine to treat osteoarthritis, and we are delighted to now be able to offer this service from our clinic.
What is Alpha-2 Macroglobulin?
Alpha-2 macroglobulin is a glycoprotein which is an innate part of the body’s immune system. It has been shown to have potent anti-inflammatory effects when injected into joints with degenerative disease. Alpha-2 can also be injected into or around soft tissue structures with inflammation, as well as used for airway conditions.
How does it work?
The process is simple- we take a sterile blood sample from your horse, spin it down using the specific centrifuge to concentrate the anti-inflammatory A2MG, and then inject that concentrated substance back into the horse wherever it is required.
The benefit of using alpha-2 is that there is very little risk of a reaction to a foreign substance, because it is simply concentrated factors from the horse’s own blood being injected back into the body. Unlike when using steroids, we do not have to be concerned about associated risk of laminitis and so this is an excellent option for our lami-prone four legged friends.
We have used the alpha-2 macroglobulin in many horses now and seen excellent responses. Attached are photos of ‘Golly’ who has multiple areas of arthritis, and has been treated with steroid in the past. We medicated Golly’s neck with alpha-2 recently and he has been going superbly since.
“Golly had the harvesting and his neck injected about 6 weeks ago, previously to this his performance had dropped off he found maintaining canter difficult, lateral work was getting harder, he would get tense roll in a ball and bounce on the spot trying to rear, he was unhappy, ok to hack, at competitions our marks had dropped off as he found things more difficult.
When he had the Alpha 2 injected he had a week of light work just hacking then we gradually introduced schooling, we have attended a couple of competitions where his marks have improved, nearing our personal best. but even better than that he maintains his frame better, canter has improved so much and he is doing his best ever lateral work, my trainer has noticed the difference now each session is own new best ever😁 I have a happy horse who has started to try harder because he can 🥰”
