27/07/2026
Alfie's Journey: Acquired Myasthenia Gravis 💜
Just 24 hours before arriving at Pride Veterinary Referrals, 7-year-old German Shepherd Alfie had gone from a happy, active dog to barely being able to stand.
After a thorough neurological examination, our team suspected acquired myasthenia gravis - a rare autoimmune disease where the body's immune system attacks the communication between nerves and muscles, causing severe muscle weakness. Chest X-rays, a neostigmine test (shown in this video) and specialised antibody testing confirmed the diagnosis.
Although treatment is available, recovery is rarely straightforward. Finding the right medication took time and Alfie experienced setbacks, including relapses, exercise intolerance and difficulty swallowing. Throughout it all, his devoted family provided exceptional home care, carefully feeding him upright, monitoring his progress and supporting him every step of the way.
Slowly, week by week, Alfie grew stronger.
One year later, we're thrilled to share that Alfie has achieved both clinical and immunological remission. His neurological examination is now completely normal, his exercise tolerance has returned, his antibody test is negative, and he's gradually coming off his medication while enjoying life to the fullest once again.
Alfie's journey is a wonderful reminder that, with early diagnosis, specialist care, dedicated owners and plenty of patience, even conditions with a guarded prognosis can have an excellent outcome.
Seeing Alfie's recovery has been one of the greatest privileges for our neurologist, Pati, and the entire Neurology team. We couldn't be happier for Alfie and his family