
30/05/2025
AWESOME NEW JOINT SUPPLEMENT - UC-II - NOW FREE!
UC-II is fab for joints:
A study pitted it (at just a 40mg dose) against a standard glucosamine and chondroitin supplement (1500mg and 1200mg, respectively) in 191 human volunteers suffering osteoarthritis pain in a randomised controlled trial.
The primary endpoint was changes in the total Western Ontario McMaster Universities Osteoarthritis(WOMAC) Index through 180 days.
At day 180, the UC-II group demonstrated a significant reduction in overall WOMAC score compared to the GC supplement (p = 0.04).
UC-II also beat standard glucosamine/chondroitin for changes in pain, stiffness and physical function.
It’s thought to act via some type of oral tolerance whereby small amounts of UC-II are taken up by the gut-associated lymphoid tissue (GALT), resulting in a downregulation of immune attacks on joint cartilage (autoimmune modulation).
What is UC-II, I hear you say?
It stands for Undenatured Type II collagen, meaning Type II collagen in its normal, undenatured, triple-helix form, not processed down into single peptides or gelatin by processing (heat or even grinding will do it).
Not that the broth-form of collagen / gelatin is not of some joint benefit, it surely is, providing all the building blocks of said collagen (like glycine and proline), necessary for cartilage repair, but the immune modulating effects of the undenatured stuff it will lack.
My God, where can we get this amazing supplement?!! I will spend anything!
No money required - it's FREE because it comes from raw meaty bones. That's where you get undenatured collagen from.
So you'll not only get fresh calcium, fresh glucosmine, chondroitin, hyaluronic acid and all the crucial joint building compounds and co factors (vitamins and mineral) but you will also get lots of UNDENATURED collagen, shown to help with osteoarthritis AND, by cleaning their teeth, you will reduce over all systemic inflammation in your pet.
If you cut these compounds out (eg by feeding kibble only and denying your dog raw meaty bones starting out in life) their joints will be weaker because of it. And when arthritic by mid age you will be sold the (grossly inferior, ultraprocessed) solution - ground up cartilage in a capsule.
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Lugo et al. (2016). Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Journal or Nutrition