27/06/2026
Another study showing the positive effects of the SGLT2 inhibitors on insulin dysregulation (EMS) in horses. While Bexagliflozin is not readily available in Australia, we use Ertugliflozin with similar results.
To reduce the chances of developing laminitis from insulin dysregulation, the use of SGLT2 inhibitors are crucial. A simple baseline blood insulin helps us understand the likelihood of the horse having insulin dysregulation and furthermore can predict the chance of developing laminitis if left untreated.
A placebo-controlled study found that bexagliflozin effectively reduced insulin concentrations in horses with naturally occurring insulin dysregulation, supporting its potential as a short-term management option for this challenging condition.
Open access article: jav.ma/bexagliflozin