24/02/2026
New peer-reviewed, randomized, placebo-controlled research shows that dogs with aggression, social anxiety, or separation anxiety given the probiotic Lactiplantibacillus plantarum LP815 experienced significant behavioral improvements in just 4 weeks. Owners reported their dogs settled faster when left alone, slept and woke more consistently, maintained steadier daily activity, and were slightly less active overall, but in a calm, alert way rather than appearing sedated.
Why LP815 is different? This next-generation probiotic naturally produces GABA (gamma-aminobutyric acid), a neurotransmitter that helps calm the nervous system by regulating nerve activity. Unlike traditional calming supplements, LP815 works through the gut–brain axis to support more lasting, natural calming effects.
LP815 clinical results in dogs (after 4 weeks):
• Reduced fear- and noise-related aggression
• More restful, consistent sleep
• Improved mood and reduced reactivity
• Better energy and emotional balance
• Faster settling after owner departure
That’s why when developed her one-of-a-kind canine probiotic, she included Lactiplantibacillus plantarum LP815™ in PRIMITIVE PROBIOTICS™ : a science-driven approach to rebuilding and maintaining your dog’s microbiome using strains inspired by wild canids, healthy domestic dogs, and living soil.
If you want to explore a science backed probiotic option for your dog, comment BETTERBELLY and we’ll DM you the link.
