16/01/2024
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IRIS CKD (International Renal Interest Society) staging is based on fasting blood creatinine concentration and blood SDMA concentration.
SDMA may be a more sensitive marker that is less impacted by loss of lean body mass.
DOGS:
πΆ If serum or plasma SDMA is persistently >18 Β΅g/dl in a dog whose creatinine is 35 Β΅g/dl in a dog whose creatinine is between 1.4 and 2.8 mg/dl (IRIS CKD stage 2 based on creatinine), this canine patient should be staged and treated as an IRIS CKD Stage 3 patient.
πΆ If serum or plasma SDMA is persistently >54 Β΅g/dl in a dog whose creatinine is between 2.9 and 5.0 mg/dl (IRIS CKD stage 3 based on creatinine), this canine patient should be staged and treated as an IRIS CKD Stage 4 patient.
CATS
πΏ If serum or plasma SDMA is persistently >18 Β΅g/dl in a cat whose creatinine is 25 Β΅g/dl in a cat whose creatinine is between 1.6 and 2.8 mg/dl (IRIS CKD stage 2 based on creatinine), this feline patient should be staged and treated as an IRIS CKD Stage 3 patient.
πΏ If serum or plasma SDMA is persistently >38 Β΅g/dl in a cat whose creatinine is between 2.9 and 5.0 mg/dl (IRIS CKD stage 3 based on creatinine), this feline patient should be staged and treated as an IRIS CKD Stage 4 patient.