14/07/2025
https://www.facebook.com/share/p/1B8392XhGm/?mibextid=wwXIfr
Researchers from Seoul, South Korea, undertook a study to assess the therapeutic effects of green-lipped mussel oil complex (GLMOC) on canine osteoarthritis (OA) and effects of dose and OA severity on treatment efficacy. Fifteen dogs were recruited and grouped into two based on OA severity. They received the recommended GLMOC dose for the first four weeks and half for the following two weeks, which was followed by a two-week withdrawal. The outcomes included the Canine Brief Pain Inventory (CBPI) score, orthopaedic assessment score (OAS), and peak vertical force (PVF). Trial outcomes indicated the CBPI score, OAS, and PVF significantly improved at week four. The treatment success rate was 40%. The improvements persisted during the reduction and withdrawal phases, but their significance reduced. The PVF (week four), CBPI score (weeks four and six), and OAS (weeks four, six and eight) significantly improved for the dogs with mild/moderate OA. The OAS significantly improved for severe OA only at week four. The results suggest GLMOC treatment provided significant pain relief and functional improvement for OA over four weeks without adverse effects. Optimal outcomes are expected in patients with mild or moderate OA treated with consistent medications.