08/09/2025
It is important as vet nurses we understand the basics regarding laboratory work and findings, so over the next few weeks we are going to start by looking at all things blood cells.
Red blood cells are the most numerous blood cell type in mammals. They are biconcave discs, providing a large surface area for gas exchange and flexibility to traverse tiny capillaries.
• Lifespan: In most mammals, erythrocytes live about 100-120 days (dogs: ~110 days, cats: ~70 days).
• Function: Their primary role is to carry oxygen from the lungs to tissues and return carbon dioxide for expulsion. This is achieved by the oxygen-carrying pigment, haemoglobin.
• Identifying Features: Mammalian RBCs lack nuclei and are uniform in size and colour (pink to red in stained smears). In non-mammalian vertebrates (birds, reptiles), RBCs are oval and nucleated.
Abnormalities:
• Anaemia: A reduction in RBC number, haemoglobin, or both. Causes include blood loss, destruction of RBCs (haemolysis), or decreased production (bone marrow problems).
• Polycythaemia: An increased number of RBCs. Can be due to dehydration or, rarely, diseases causing excessive RBC production.
• Shape Abnormalities (Poikilocytosis): RBCs may become misshapen due to various diseases (e.g., echinocytes, spherocytes, schistocytes).
• Colour Abnormalities: Hypochromia (pale cells) suggests iron deficiency; polychromasia (bluish tint) indicates young RBCs (reticulocytes).